July 3, 2011

Gene Editing

One of the problems with curing genetic diseases by genetic engineering is that the easiest method is randomly inserting the correct gene. But then you not only don’t take advantage of the natural gene function regulators, but you run the risk of disrupting other genetic elements, with a consequent risk […]
June 18, 2011

Smooth Joints

One of the many issues of growing old is the slow deterioration in cartilage. Cartilage provides a “non-stick” surface to lubricate your joints, and while it is a remarkable material (often lasts a lifetime of wear!), it has little if any regenerative power. Hence the osteoarthritis that plagues so many […]
June 11, 2011

Heart to Heart

A paper in Nature, summarised in The Scientist, reports success in making progenitor cells, that naturally exist in the outer layer of heart tissue, proliferate, migrate into heart muscle and transform into heart muscle cells (cardiomyocytes). The research in mice “suggests that the human heart could be encouraged to repair itself […]
May 22, 2011

Live Liver Transplants

While lab-grown skin has been around for a while (relatively speaking!) and artifical bladders have already been used medically, the problem with growing solid organs is that their three-dimensional structure can be important, both in terms of localisation of cells with different specialisations and the blood supply to the organ. […]
May 21, 2011

Life Extension: Ending It All

Telomeres are the “caps” on the ends of chromosomes that keep things functioning smoothly. Normally, each time a cell divides its telomeres get shorter, until eventually the cells can no longer function. The enzyme telomerase can restore the telomeres (that is how many cancer cells achieve their self-destructive “immortality”). By […]
May 21, 2011

Do You Wanna Live Forever?

In the immortal words of Starship Troopers (originally of a military commander in the 20th century, I believe): “Do you wanna live forever?” A while ago at our monthly philosophy meetings, my talk was life extension: how for the first time in human history, technology was advancing at a sufficient […]